Andrea Gaedigk Selected Research

Cytochrome P-450 CYP2D6 (CYP2D6)

1/2022	CYP2D6 gene resequencing in the Malagasy, a population at the crossroads between Asia and Africa: a pilot study.
1/2021	CYP2D6 Genetic Variation and Its Implication for Vivax Malaria Treatment in Madagascar.
11/2020	Transfer learning enables prediction of CYP2D6 haplotype function.
1/2020	CYP2D6 Predicts Plasma Donepezil Concentrations in a Cohort of Thai Patients with Mild to Moderate Dementia.
1/2020	Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group.
1/2018	Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy.
1/2018	Impact of CYP2D6 on venlafaxine metabolism in Trinidadian patients with major depressive disorder.
4/2017	Impact of CYP2D6 genotype on amitriptyline efficacy for the treatment of diabetic peripheral neuropathy: a pilot study.
2/2016	Role of Pharmacogenetics in Improving the Safety of Psychiatric Care by Predicting the Potential Risks of Mania in CYP2D6 Poor Metabolizers Diagnosed With Bipolar Disorder.
1/2016	Pharmacogenetics to prevent maniac affective switching with treatment for bipolar disorder: CYP2D6.

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Andrea Gaedigk Research Topics

Disease

5	Infections 01/2021 - 05/2010
3	Schizophrenia (Dementia Praecox) 01/2021 - 10/2008
3	Pain (Aches) 01/2021 - 01/2007
3	Body Weight (Weight, Body) 05/2014 - 08/2002
2	Vivax Malaria 01/2022 - 01/2021
2	Esophagitis 01/2021 - 01/2021
2	Gastroesophageal Reflux (GERD) 01/2021 - 08/2003
2	Drug-Related Side Effects and Adverse Reactions 11/2020 - 01/2013
2	Hypercholesterolemia 01/2020 - 01/2019
2	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2019 - 01/2016
2	Breast Neoplasms (Breast Cancer) 01/2018 - 09/2010
2	Cerebral Palsy (Spastic Diplegia) 01/2018 - 05/2014
2	Major Depressive Disorder (Major Depressive Disorders) 01/2018 - 06/2006
2	Hypertension (High Blood Pressure) 01/2017 - 12/2004
2	Bipolar Disorder (Manic Depressive Psychosis) 02/2016 - 01/2016
2	Poisoning 01/2007 - 08/2006
1	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 01/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Muscular Diseases (Myopathy) 01/2022
1	Chronic Pain 10/2021
1	Coumarin Resistance 01/2021
1	Autism Spectrum Disorder 01/2021
1	Genetic Risk Score 01/2021
1	Autistic Disorder (Autism) 01/2021
1	Duodenal Ulcer (Curling's Ulcer) 01/2021
1	Gastritis 01/2021
1	Malaria 01/2021
1	Opioid-Related Disorders (Opiate Addiction) 01/2021
1	Obesity 01/2021
1	Stevens-Johnson Syndrome (Lyell's Syndrome) 01/2021
1	Mood Disorders (Mood Disorder) 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2021
1	Inborn Urea Cycle Disorders 01/2021
1	Tourette Syndrome (Tourette's Syndrome) 11/2020
1	Confusion (Bewilderment) 01/2020
1	Dementia (Dementias) 01/2020
1	Thrombosis (Thrombus) 01/2019
1	Hemorrhage 01/2019
1	Muscle Spasticity (Spastic) 01/2018
1	Peripheral Nervous System Diseases (PNS Diseases) 04/2017
1	Psychotic Disorders (Schizoaffective Disorder) 02/2016
1	Anxiety Disorders (Anxiety Disorder) 02/2016
1	Mania (Manias) 02/2016
1	Parkinson Disease (Parkinson's Disease) 09/2012

Drug/Important Bio-Agent (IBA)

15	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2022 - 03/2004
10	Pharmaceutical PreparationsIBA 01/2022 - 03/2008
4	Codeine (Codeine Phosphate)FDA LinkGeneric 01/2021 - 08/2006
4	EnzymesIBA 09/2012 - 07/2003
3	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2021 - 10/2008
3	Antipsychotic Agents (Antipsychotics)IBA 01/2021 - 10/2008
3	Omeprazole (Prilosec)FDA LinkGeneric 09/2004 - 08/2002
2	Rosuvastatin Calcium (Crestor)FDA Link 01/2022 - 01/2020
2	Primaquine FDA Link 01/2022 - 01/2020
2	Pravastatin (Pravachol)FDA LinkGeneric 01/2022 - 01/2019
2	efavirenz (Sustiva)FDA Link 01/2021 - 10/2019
2	Antidepressive Agents (Antidepressants)IBA 01/2021 - 07/2010
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 08/2005
2	Atomoxetine Hydrochloride (Strattera)FDA LinkGeneric 01/2019 - 01/2016
2	Warfarin (Coumadin)FDA LinkGeneric 01/2019 - 01/2017
2	Cytochrome P-450 CYP2C19IBA 01/2018 - 09/2004
2	Baclofen FDA LinkGeneric 01/2018 - 05/2014
2	DNA (Deoxyribonucleic Acid)IBA 07/2010 - 10/2008
2	Morphine (MS Contin)FDA LinkGeneric 01/2007 - 08/2006
1	CholesterolIBA 01/2022
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022
1	Simvastatin (Zocor)FDA LinkGeneric 01/2022
1	Atorvastatin (Lipitor)FDA Link 01/2022
1	Fluvastatin FDA Link 01/2022
1	Lovastatin (Mevacor)FDA LinkGeneric 01/2022
1	pitavastatin (itavastatin)FDA Link 01/2022
1	Opioid Analgesics (Opioids)IBA 10/2021
1	Valproic Acid (Depakote)FDA LinkGeneric 01/2021
1	cytochrome P-450 CYP2C subfamilyIBA 01/2021
1	AcidsIBA 01/2021
1	Analgesics (Analgesic Drugs)IBA 01/2021
1	Blood Coagulation Factors (Coagulation Factor)IBA 01/2021
1	Ketamine FDA LinkGeneric 01/2021
1	Methadone (Dolophine)FDA LinkGeneric 01/2021
1	Phenytoin (Dilantin)FDA LinkGeneric 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	ProlactinIBA 01/2021
1	HLA-B Antigens (HLA-B)IBA 01/2021
1	Bupropion (Wellbutrin)FDA LinkGeneric 01/2021
1	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2021
1	A-Form DNA (A-DNA)IBA 01/2021
1	Proton Pump InhibitorsIBA 01/2021
1	Pimozide (Orap)FDA Link 11/2020
1	Dopamine AntagonistsIBA 11/2020
1	Chloroquine (Aralen)FDA LinkGeneric 01/2020
1	Donepezil (Aricept)FDA LinkGeneric 01/2020
1	Reverse Transcriptase InhibitorsIBA 10/2019
1	4-hydroxy-N-desmethyltamoxifenIBA 01/2018
1	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 01/2018
1	Cytochrome P-450 CYP2D6 InhibitorsIBA 01/2018
1	Tamoxifen FDA LinkGeneric 01/2018
1	Amitriptyline (Elavil)FDA LinkGeneric 04/2017
1	Cytochrome P-450 CYP2C9IBA 01/2017
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 02/2016
1	ProdrugsIBA 02/2011

Therapy/Procedure

4	Therapeutics 01/2022 - 04/2017